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This Week in PLoS Medicine: Drug resistance in Ethiopia; Preterm births in Mexico; Nuclear receptors in lung cancer

Image Credit: Scott Robinson

Three new articles were published this week in PLoS Medicine.

Jeremy Keenan and colleagues report their cluster-randomized clinical trial in Ethiopia that found nasopharyngeal pneumococcal resistance to macrolides to be significantly higher in communities randomized to receive azithromycin then among untreated control communities.

Joshua Salomon and colleagues performed a cost-effectiveness analysis using health and economic outcomes following preterm birth in Mexico and show that neonatal intensive care provided high value for the money in this setting.

David Mangelsdorf and colleagues show that nuclear receptor expression is strongly associated with clinical outcomes of lung cancer patients, and that this expression profile is a potential prognostic signature for lung cancer patient survival time, particularly for individuals with early stage disease.

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