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This Week in PLoS Medicine: 4ABC & malaria; Xpert diagnosis; Preterm birth outcomes; Global health education

Michael Morris General

Image Credit: Mishel Churkin

Four new articles published this week in PLoS Medicine:

The Four Artemisinin-Based Combinations (4ABC) Study Group reports a randomized, non-inferiority trial comparing the efficacy and safety of four ACTs in children with mild Plasmodium falciparum malaria from seven sub-Saharan African countries.

A cost-effectiveness study by Frank Cobelens and colleagues reveals that Xpert MTB/RIF is a cost-effective method of tuberculosis diagnosis suitable for use in low- and middle-income settings.

Using data collected in a follow-up to a randomized trial, Melissa Gladstone and colleagues show that during the first two years of life, infants born preterm in southern Malawi are disadvantaged in terms of mortality, growth, and development.

Vanessa Kerry and colleagues discuss how to manage the unprecedented growth in and demand for global health programs in the United States, Europe, and other high-income countries.

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