PLOS Resources on Ebola
Virginia Barbour, Medicine & Biology Editorial Director at PLOS, on the urgent need for Open Access research into the Ebola outbreak in West Africa.
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This post was updated on November 21st to include new research published in PLOS Pathogens and new commentary published in PLOS Currents Outbreaks.
This post was updated on September 19th, October 9th, 15th and 17th, and November 2nd, 3rd, 13th and 14th to include new content from PLOS Currents Outbreaks, PLOS Neglected Tropical Diseases and Speaking of Medicine.
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The current Ebola outbreak in West Africa probably began in Guinea in 2013, but it was only recognized properly in early 2014 and shows, at the time of writing, no sign of subsiding. The continuous human-to-human transmission of this new outbreak virus has become increasingly worrisome.
Analyses thus far of this outbreak mark it as the most serious in recent years and the effects are already being felt far beyond those who are infected and dying; whole communities in West Africa are suffering because of its negative effects on health care and other infrastructures. Globally, countries far removed from the outbreak are considering their local responses, were Ebola to be imported; and the ripple effects on the normal movement of trade and people are just becoming apparent.
There is an urgent need for research into all aspects of this Ebola outbreak. PLOS is addressing this need today through two channels. First is the rapid publication of important early research in PLOS Currents Outbreaks. The second is a new PLOS Collection that pulls together all the current published articles in the PLOS corpus, which are, like all our content, freely and openly available for download, use and reuse. The Collection is available on Flipboard as well as being described below.
The putative first virus introduction and epicenter are in the vicinity of the town of Guéckédou in the Guinea Forest Region. CDC: http://goo.gl/HH4HQU
doi:10.1371/journal.pntd.0003056.g001
All of the PLOS publications are open to submissions on Ebola. In PLOS Currents, an integrated direct-authoring and publishing platform, Outbreaks affords authors an accelerated review and publication process. The seven PLOS journals — PLOS Biology, Computational Biology, Genetics, Medicine, Neglected Tropical Diseases, ONE, and Pathogens – also consider research on Ebola within each journal’s particular scope. To expedite publication in the appropriate venue, editors of one journal may recommend facilitated transfer of submissions to another of the journals or to PLOS Currents: Outbreaks.
The new Ebola Collection will be regularly updated with new content from all of all of the PLOS publications Please contact collections@plos.org with enquiries.
The Current Outbreak
Gerardo Chowell, Lone Simonsen, Cécile Viboud, Yang Kuang
Commentary | 20 Nov 2014 | PLOS Currents Outbreaks
A Three-Scale Network Model for the Early Growth Dynamics of 2014 West Africa Ebola Epidemic
Maria A. Kiskowski
Research | 13 Nov 2014 | PLOS Currents Outbreaks
What Factors Might Have Led to the Emergence of Ebola in West Africa?
K.A. Alexander, C.E. Sanderson, M. Marathe, B.L. Lewis, C.M. Rivers, J. Shaman, J.M. Drake, E. Lofgren, V.M. Dato, M.C. Eisenberg, and S. Eubank
Commentary | 11 Nov 2014 | PLOS Neglected Tropical Diseases (early publication on Speaking of Medicine)
Maximilian Haeussler, Donna Karolchik, Hiram Clawson, Brian J Raney, Kate R. Rosenbloom, Pauline A. Fujita, Angie S. Hinrichs, Matthew L Speir, Chris Eisenhart, Ann S. Zweig, David Haussler, W. James Kent
Research | 7 Nov 2014 | PLOS Currents Outbreaks
Conservancy of mAb Epitopes in Ebolavirus Glycoproteins of Previous and 2014 Outbreaks
Julia Ponomarenko, Kerrie Vaughan, Alessandro Sette and Sebastian Maurer-Stroh
Research | 3 Nov 2014 | PLOS Currents Outbreaks
Social Pathways for Ebola Virus Disease in Rural Sierra Leone, and some Implications for Containment
Paul Richards, Joseph Amara, Mariane C Ferme, Prince Kamara, Esther Mokuwa, Amara Idara Sheriff, Roland Suluku,and Maarten Voors
Commentary | 31 Oct 2014 | PLOS Neglected Tropical Diseases (early publication on Speaking of Medicine)
Ebola has Taught us a Crucial Lesson about our Views of “Irrational” Health Behaviors
Sara Gorman
Blog | 22 Oct 2014 | Speaking of Medicine
Modeling the Impact of Interventions on an Epidemic of Ebola in Sierra Leone and Liberia
Caitlin M. Rivers, Eric T. Lofgren, Madhav Marathe, Stephen Eubank, Bryan L. Lewis
Research Article | 16 Oct 2014 | PLOS Currents Outbreaks
On the Quarantine Period for Ebola Virus
Charles N. Haas
Research Article | 14 Oct 2014 | PLOS Currents Outbreaks
Insights into the Early Epidemic Spread of Ebola in Sierra Leone Provided by Viral Sequence Data
Tanja Stadler, Denise Kühnert, David A. Rasmussen, Louis du Plessis
Research Article | 6 Oct 2014 | PLOS Currents Outbreaks
Commentary: Containing the Ebola Outbreak – the Potential and Challenge of Mobile Network Data
Amy Wesolowski, Caroline O. Buckee, Linus Bengtsson, Erik Wetter, Xin Lu, Andrew J. Tatem
Commentary | 29 Sep 2014 | PLOS Currents Outbreaks
Temporal Variations in the Effective Reproduction Number of the 2014 West Africa Ebola Outbreak
Sherry Towers, Oscar Patterson-Lomba, Carlos Castillo-Chavez
Research Article | 18 Sep 2014 | PLOS Currents Outbreaks
Grazia Caleo
Blog | 18 Sep 2014 | Speaking of Medicine
David Fisman, Edwin Khoo, Ashleigh Tuite
Research Article | 8 Sep 2014 | PLOS Currents Outbreaks
Assessing the International Spreading Risk Associated with the 2014 West African Ebola Outbreak
Marcelo F. C. Gomes, Ana Pastore y Piontti, Luca Rossi, Dennis Chao, Ira Longini, M. Elizabeth Halloran, Alessandro Vespignani
Research Article | 2 Sep 2014 | PLOS Currents Outbreaks
Estimating the Reproduction Number of Ebola Virus (EBOV) During the 2014 Outbreak in West Africa
Christian L. Althaus
Research Article | 2 Sep 2014 | PLOS Currents Outbreaks
The Global Response to the Ebola Fever Epidemic: What Took So Long?
Mark J. Siedner, John D. Kraemer
Blog | 22 August 2014 | Speaking of Medicine
Ebola: Liberians Destined for Extinction
Gondah Lekpeh
Blog | 21 August 2014 | Speaking of Medicine
Outbreak of Ebola Virus Disease in Guinea: Where Ecology Meets Economy
Daniel G. Bausch, Lara Schwarz
Editorial | published 31 Jul 2014 | PLOS Neglected Tropical Diseases
Clock Rooting Further Demonstrates that Guinea 2014 EBOV is a Member of the Zaïre Lineage
Sébastien Calvignac-Spencer, Jakob M. Schulze, Franziska Zickmann, Bernhard Y. Renard
Research Article | 16 Jun 2014 | PLOS Currents Outbreaks
Phylogenetic Analysis of Guinea 2014 EBOV Ebolavirus Outbreak
Gytis Dudas, Andrew Rambaut
Research Article | 2 May 2014 | PLOS Currents Outbreaks
Previous Outbreaks
Rosalind Parkes-Ratanshi, Ali Elbireer, Betty Mbambu, Faridah Mayanja, Alex Coutinho, Concepta Merry
Research Article | published 09 Jul 2014 | PLOS ONE
Hospital-Based Surveillance for Viral Hemorrhagic Fevers and Hepatitides in Ghana
Joseph Humphrey Kofi Bonney, Mubarak Osei-Kwasi, Theophilus Korku Adiku, Jacob Samson Barnor, Robert Amesiya, Chrysantus Kubio, Lawson Ahadzie, Stephan Ölschläger, Michaela Lelke, Beate Becker-Ziaja, Meike Pahlmann, Stephan Günther
Research Article | published 19 Sep 2013 | PLOS Neglected Tropical Diseases
Paul Roddy, Natasha Howard, Maria D. Van Kerkhove, Julius Lutwama, Joseph Wamala, Zabulon Yoti, Robert Colebunders, Pedro Pablo Palma, Esther Sterk, Benjamin Jeffs, Michel Van Herp, Matthias Borchert
Research Article | published 28 Dec 2012 | PLOS ONE
Ebola and Marburg Hemorrhagic Fevers: Neglected Tropical Diseases?
Adam MacNeil, Pierre E. Rollin
Review | published 26 Jun 2012 | PLOS Neglected Tropical Diseases
Newly Discovered Ebola Virus Associated with Hemorrhagic Fever Outbreak in Uganda
Jonathan S. Towner, Tara K. Sealy, Marina L. Khristova, César G. Albariño, Sean Conlan, Serena A. Reeder, Phenix-Lan Quan, W. Ian Lipkin, Robert Downing, Jordan W. Tappero, Samuel Okware, Julius Lutwama, Barnabas Bakamutumaho, John Kayiwa, James A. Comer, Pierre E. Rollin, Thomas G. Ksiazek, Stuart T. Nichol
Research Article | published 21 Nov 2008 | PLOS Pathogens
Effective Post-Exposure Treatment of Ebola Infection
Heinz Feldmann, Steven M Jones, Kathleen M Daddario-DiCaprio, Joan B Geisbert, Ute Ströher, Allen Grolla, Mike Bray, Elizabeth A Fritz, Lisa Fernando, Friederike Feldmann, Lisa E Hensley, Thomas W Geisbert
Research Article | published 19 Jan 2007 | PLOS Pathogens
Nancy J Sullivan, Thomas W Geisbert, Joan B Geisbert, Devon J Shedlock, Ling Xu, Laurie Lamoreaux, Jerome H. H. V Custers, Paul M Popernack, Zhi-Yong Yang, Maria G Pau, Mario Roederer, Richard A Koup, Jaap Goudsmit, Peter B Jahrling, Gary J Nabel
Research Article | published 16 May 2006 | PLOS Medicine
Wave-Like Spread of Ebola Zaire
Peter D Walsh, Roman Biek, Leslie A Real
Research Article | published 25 Oct 2005 | PLOS Biology
Containing the Threat—Don’t Forget Ebola
Jonathan Cohen
Perspective | published 28 Dec 2004 | PLOS Medicine
Pathogenesis
Shed GP of Ebola Virus Triggers Immune Activation and Increased Vascular Permeability
Beatriz Escudero-Pérez, Valentina A. Volchkova, Olga Dolnik, Philip Lawrence, Viktor E. Volchkov
Research Article | published 20 Nov 2014 | PLOS Pathogens
Rajini Mudhasani, Krishna P. Kota, Cary Retterer, Julie P. Tran, Chris A. Whitehouse, Sina Bavari
Research Article | published 21 Aug 2014 | PLOS Neglected Tropical Diseases
Sara Garamszegi, Judy Y. Yen, Anna N. Honko, Joan B. Geisbert, Kathleen H. Rubins, Thomas W. Geisbert, Yu Xia, Lisa E. Hensley, John H. Connor
Research Article | published 31 Jul 2014 | PLOS Neglected Tropical Diseases
Pierre Becquart, Tanel Mahlakõiv, Dieudonné Nkoghe, Eric M. Leroy
Research Article | published 10 Jun 2014 | PLOS ONE
Karen A. O. Martins, Jesse T. Steffens, Sean A. van Tongeren, Jay B. Wells, Alison A. Bergeron, Samuel P. Dickson, John M. Dye, Andres M. Salazar, Sina Bavari
Research Article | published 24 Feb 2014 | PLOS ONE
Masfique Mehedi, Thomas Hoenen, Shelly Robertson, Stacy Ricklefs, Michael A. Dolan, Travis Taylor, Darryl Falzarano, Hideki Ebihara, Stephen F. Porcella, Heinz Feldmann
Research Article | published 17 Oct 2013 | PLOS Pathogens
A Fusion-Inhibiting Peptide against Rift Valley Fever Virus Inhibits Multiple, Diverse Viruses
Jeffrey W. Koehler, Jeffrey M. Smith, Daniel R. Ripoll, Kristin W. Spik, Shannon L. Taylor, Catherine V. Badger, Rebecca J. Grant, Monica M. Ogg, Anders Wallqvist, Mary C. Guttieri, Robert F. Garry, Connie S. Schmaljohn
Research Article | published 12 Sep 2013 | PLOS Neglected Tropical Diseases
Joseph E. Blaney, Andrea Marzi, Mallory Willet, Amy B. Papaneri, Christoph Wirblich, Friederike Feldmann, Michael Holbrook, Peter Jahrling, Heinz Feldmann, Matthias J. Schnell
Research Article | published 30 May 2013 | PLOS Pathogens
A Systematic Screen of FDA-Approved Drugs for Inhibitors of Biological Threat Agents
Peter B. Madrid, Sidharth Chopra, Ian D. Manger, Lynne Gilfillan, Tiffany R. Keepers, Amy C. Shurtleff, Carol E. Green, Lalitha V. Iyer, Holli Hutcheson Dilks, Robert A. Davey, Andrey A. Kolokoltsov, Ricardo Carrion, Jean L. Patterson, Sina Bavari, Rekha G. Panchal, Travis K. Warren, Jay B. Wells, Walter H. Moos, RaeLyn L. Burke, Mary J. Tanga
Research Article | published 05 Apr 2013 | PLOS ONE
Laura J. Sherwood, Andrew Hayhurst
Research Article | published 05 Apr 2013 | PLOS ONE
Antigenic Subversion: A Novel Mechanism of Host Immune Evasion by Ebola Virus
Gopi S. Mohan, Wenfang Li, Ling Ye, Richard W. Compans, Chinglai Yang
Research Article | published 13 Dec 2012 | PLOS Pathogens
The Ebola Virus Glycoprotein Contributes to but Is Not Sufficient for Virulence In Vivo
Allison Groseth, Andrea Marzi, Thomas Hoenen, Astrid Herwig, Don Gardner, Stephan Becker, Hideki Ebihara, Heinz Feldmann
Research Article | published 02 Aug 2012 | PLOS Pathogens
The Organisation of Ebola Virus Reveals a Capacity for Extensive, Modular Polyploidy
Daniel R. Beniac, Pasquale L. Melito, Shauna L. deVarennes, Shannon L. Hiebert, Melissa J. Rabb, Lindsey L. Lamboo, Steven M. Jones, Timothy F. Booth
Research Article | published 11 Jan 2012 | PLOS ONE
Victoria Wahl-Jensen, Sabine Kurz, Friedericke Feldmann, Lukas K. Buehler, Jason Kindrachuk, Victor DeFilippis, Jean da Silva Correia, Klaus Früh, Jens H. Kuhn, Dennis R. Burton, Heinz Feldmann
Research Article | published 18 Oct 2011 | PLOS Neglected Tropical Diseases
Yoshimi Tsuda, Patrizia Caposio, Christopher J. Parkins, Sara Botto, Ilhem Messaoudi, Luka Cicin-Sain, Heinz Feldmann, Michael A. Jarvis
Research Article | published 09 Aug 2011 | PLOS Neglected Tropical Diseases
Serologic Cross-Reactivity of Human IgM and IgG Antibodies to Five Species of Ebola Virus
Adam MacNeil, Zachary Reed, Pierre E. Rollin
Research Article | published 07 Jun 2011 | PLOS Neglected Tropical Diseases
Asuka Nanbo, Masaki Imai, Shinji Watanabe, Takeshi Noda, Kei Takahashi, Gabriele Neumann, Peter Halfmann, Yoshihiro Kawaoka
Research Article | published 23 Sep 2010 | PLOS Pathogens
Mohammad F. Saeed, Andrey A. Kolokoltsov, Thomas Albrecht, Robert A. Davey
Research Article | published 16 Sep 2010 | PLOS Pathogens
Joseph R. Francica, Angel Varela-Rohena, Andrew Medvec, Gabriela Plesa, James L. Riley, Paul Bates
Research Article | published 09 Sep 2010 | PLOS Pathogens
Demonstration of Cross-Protective Vaccine Immunity against an Emerging Pathogenic Ebolavirus Species
Lisa E. Hensley, Sabue Mulangu, Clement Asiedu, Joshua Johnson, Anna N. Honko, Daphne Stanley, Giulia Fabozzi, Stuart T. Nichol, Thomas G. Ksiazek, Pierre E. Rollin, Victoria Wahl-Jensen, Michael Bailey, Peter B. Jahrling, Mario Roederer, Richard A. Koup, Nancy J. Sullivan
Research Article | published 20 May 2010 | PLOS Pathogens